The Architect of the Nuclear Age – Does the Expansion of Knowledge Always Benefit Humanity?

The Architect of the Nuclear Age – Does the Expansion of Knowledge Always Benefit Humanity?

Referred to as the “architect of the nuclear age,” Enrico Fermi was a nuclear physicist, a Nobel Prize winner, and a Freemason. Throughout his prolific career, he made substantial contributions to the fields of Quantum Theory, Statistical Mechanics, and Nuclear and Particle Physics. Fermi excelled at both experimental and theoretical work – a distinction accomplished by few physicists.

He labored for the betterment of humanity, yet his research ultimately led to the creation and utilization of the atomic bombs, which killed over 200,000 citizens of Hiroshima and Nagasaki, Japan. Brother Enrico was adamantly opposed to the utilization of the hydrogen bomb, yet he ultimately argued for the development of knowledge regardless of the consequences of the use of that knowledge.

Early Years in Italy

Born in Rome in 1901, Enrico Fermi’s fascination with Physics began at age 14 following the tragic death of his older brother, Giulio. Distraught after losing his brother, he went to a local market and found two physics textbooks written by a Jesuit physicist in 1840. Despite the fact that the books were written in Latin, Fermi read them cover to cover. From that point on, Enrico’s passion for physics became the focal point of his life.

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His understanding was so advanced in the subject that his entrance essay for the University of Pisa was deemed equivalent to the work of a doctoral student. There he received his undergraduate and doctoral degrees, and he published his first important scientific work in 1922 – his year of graduation.

Enrico Fermi became a Freemason joining the Adriano Lemmi Lodge in Rome, under the Gran Loggia d’italia di Piazza del Geso.  His intellectual curiosity made him a natural fit for the studies of Freemasonry, and he rose to the degree of Master Mason in 1923. His climb towards greatness continued as he was appointed Professor of Theoretical Physics at the University of Rome at the age of 24.

In the 1930s, he conducted a series of experiments to study the impacts of bombarding various elements with neutrons. This work led to the successful splitting of an Uranium atom for which he was awarded the Nobel Prize for Physics in 1938. Fearing for the safety of his Jewish wife, Fermi began searching for an escape from the impending genocide. Soon after, Enrico and Laura emigrated to the United States, fleeing the Fascist Regime’s take over of Italy.

Emigration to the United States 

Upon the discovery of nuclear fission, he went to the University of Chicago and later to Los Alamos to serve as a general consultant. Brother Fermi contributed significantly to the Manhattan Project. As a leading member of chicago1first-reactionthe Manhattan Project, Brother Fermi worked on the development of nuclear energy and the atomic bomb although he was a vocal critic of the use of the technology as a military weapon.

The Royal Society

Did Brother Fermi’s Masonic career continue in his participation in the Royal Society? Some Masonic Scholars have explored the hypothesis that modern Freemasonry was instituted in the 17th century by a set of philosophers and scientists who organized it under the title of the “Royal Society.” This political and philosophical club, subsequently referred to under many other names including the ” Royal Society of Sciences,” had many ties to the ancient fraternity of Freemasonry.  The Royal Society is known today as the United Kingdom’s National Academy of Science. Recently celebrating its 350th anniversary, the Library and Museum of Freemasonry held a special exhibition focused on the extraordinary number of Freemasons who have been Fellows of this august body since its inception.

Hundreds of Royal Society Fellows have belonged to the Craft, including several royals such as King George IV, Oscar I of Sweden and Norway, and enricofermiH.R.H. the Duke of Kent. Other notable members of the society include Sir Winston Churchill, Voltaire, Benjamin Franklin, and Edward Jenner.

Brother Fermi was elected Fellow of the Royal Society on April 27, 1950. In his later years, he did important work in particle physics and was an inspiring teacher at the University of Chicago. Unfortunately, in 1954 at age 54, Brother Enrico died of stomach cancer due to his exposure to radiation in his experiments. His legacy of service to Humanity continues long after his death.

Fermi stated, “Whatever Nature has in store for mankind, unpleasant as it may be, men must accept for ignorance is never better than knowledge.” Does the expansion of knowledge, even when applied to controversial ends, always benefit humanity?

 

Seeking the Light: Innovative Cures for Neurological Disorders

Seeking the Light: Innovative Cures for Neurological Disorders

The Human brain and nervous system form an intricate matrix of electrical signals that coordinate our thoughts, emotions, memories, senses, speech, and movement. Over a billion people worldwide have a form of brain disorder that incapacitates them in some manner. Each year, millions of Americans are diagnosed with an inherited condition that impacts their nervous system. Known as Neurogenetic diseases, these conditions are primarily caused by an alteration, or mutation, in the individual’s Deoxyribonucleic acid (DNA). At a cost of over $1 trillion a year, researchers and companies have a tremendous incentive to find cures for these diseases of the brain and nervous system.

Could light-seeking organisms, such as algae, provide the missing link in curing these debilitating diseases?

Neurogenetic Diseases

Billions of neurons make up the brain and form an interconnected network which communicates using chemicals called neurotransmitters. The correct functioning of this complex neural network is necessary for activitiesdna-editing such as thinking, walking, and talking. Neurogenetic disease can lead to the misfiring of neurons and can lead to irreversible degeneration of specific neurons.

Affecting individuals of all ages, neurogenetic diseases are typically chronic and debilitating. In the most extreme disorders, the impacts are degenerative and reduce the individual’s lifespan. Scientists classify neurogenetic diseases into two categories: monogenetic and complex. Disorders caused by a mutation in a single gene are referred to as “monogenetic diseases,” and  include Huntington’s disease, myotonic dystrophy, Rett syndrome and fragile X syndrome. In Monogenic diseases, a single-gene mutation causes certain neurons in the central or the peripheral nervous system to develop abnormally or function poorly. In “complex diseases” such as Parkinson’s or Alzheimer’s, disorders can be caused by mutations in multiple genes with additional environmental factors contributing to the development of the disease.

Gene Therapy

Individuals diagnosed with a neurogenetic disease live with a severe, often times progressive, disability. In degenerative neurogenetic disorders, the ability to move or talk can deteriorate thereby decreasing an individual’s independence and quality of life. In some diseases, cognitive functioning also declines which impacts the ability to reason, understand situations, and remhuman-dnaember friends, family, and past events.

Up to the 1980’s, neurogenetic diseases could be diagnosed, but little could be done to prevent the onset or progression of the diseases. Breakthroughs in understanding the human genome, the DNA sequence, has brought new hopes to those dealing with neurogenetic diseases. Gene therapy introduces new genetic material to cells to replace missing or malfunctioning genes. Previously existing only in the realm of science fiction, gene therapy has produced promising results in treating neurological diseases.

Optogenetics and Algae

Light seeking organisms, such as algae, are currently being utilized and studied by researchers in the hopes of providing a breakthrough in genetic therapies in neurological disorders. Algae needs sunlight to complete its cycle of photosynthesis: converting carbon dioxide and water into sugar which feeds the organism. Algae senses and moves towards the light via phototaxis. It is this desire for light which has made chlamydomonas reinhardtii, a single-celled alga, the focus of cutting edge reCross_section_of_a_Chlamydomonas_reinhardtii_algae_cellsearch in treating disorders of the brain and nervous system. Chlamydomonas proteins, called channelrhodopsins, were discovered on an alga’s eyespot by a research team at the Texas Health Science Center.

Optogenetics uses light to control neurons which have been genetically sensitized to light. While brain cells are not sensitive to light, by introducing light-sensitive proteins into specific types of neurons, scientists can selectively control the modified neurons by shining light into the brain. Dr. Edward Boyden, an Associate Professor of Biological Engineering and Brain and Cognitive Sciences at MIT, along with his team, envisioned a mechanism for modifying neurons.

His team spliced light-sensitive DNA from the alga into a virus, known as a gene therapy vector, which is then introduced into the body of an individual. His colleague, Dr. Feng Zhang, described the process stating, “My first challenge was to figure out a way to put channelrhodopsin-2 into neurons reliably and safely. I modified the HIV virus so that rather than delivering viral content into infected cells, the modified virus would deliver a gene for the light-sensitive protein.” Thus, through the use of algae in Optogenetics, scientists are developing innovative advancements in treating disorders including Parkinson’s, schizophrenia, autism, and depression.

Freemasonry and Seeking the Light

Freemasons seek the light to enable discovery, to gain knowledge, and to dispel ignorance. The absence of light impairs one’s ability to see and keeps tBlue Light Masoniche individual in a state of darkness and ignorance.

The Ancient Mysteries, from which Freemasonry has derived many of its teachings, developed the concept of Light as a symbol of Knowledge and Truth. Whether catalyzed by an individual’s desire for wisdom or algae’s desire to complete its cycle of photosynthesis, the search for light is truly beneficial for all.